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A 2025 University of Virginia study concluded that while GLP-1 drugs significantly reduce body weight and adiposity, they do so "with no clear evidence of cardiorespiratory fitness enhancement"a critical finding given that cardiorespiratory fitness is among the most potent predictors of all-cause and cardiovascular mortality [48]

Supplied as a lyophilised powder in a sealed laboratory vial, third-party HPLC-verified to greater than 99% purity, with a batch-specific Certificate of Analysis available on request

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