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10.1016/b978-0-12-813442-9.00007-9 25 HeubergerJ

Though gastrin-17 possesses a distinct amino acid sequence and lacks the methionine after TYS, surprisingly, the TYS residue of gastrin-17 inserts into the same hydrophobic pocket of CCK2R as that of CCK-8, except that gastrin-17 interacts more extensively with CCK2R, including F110 2.60 P114 2.64 , F120 ECL1 , V198 ECL2 , Q204 ECL2 , and S368 7.31 (Fig