doi: 10.1038/s41380-020-00952-8
At 68 weeks, participants taking 2.4 mg of semaglutide (Wegovy) weekly lost 15.8% of their body weight, compared to 6.4% for participants taking 3 mg of liraglutide (Saxenda)
Semaglutide (Red Ocean) : High demand and high competition
Mechanism of Action Melanogenesis Stimulation: Activation of MC1R stimulates the synthesis and release of eumelanin (the protective, dark pigment, typically black/brown), as opposed to pheomelanin (the red/yellow pigment)
[1] The medication does not chemically interact with capsaicin or other compounds found in chilli peppers, hot sauces, or spiced dishes
This phase II trial demonstrates that enobosarm, a selective AR modulator, shows anti-tumour activity and clinical benefit in women in postmenopause with ER-positive, HER2-negative and AR-positive advanced breast cancer, supporting further investigation of AR activation as a therapeutic strategy