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The copper-bound tripeptide (glycyl-L-histidyl-L-lysine) has an extraordinarily high copper binding affinity with a pK of 16.44, which is approximately 10 million times higher than other tripeptides

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The competitive advantage of GHK-Cu lies not in marketing hyperbole but in its broad transcriptional reach modulating over 4,000 genes linked to wound healing, oxidative stress resistance, and extracellular matrix homeostasis