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Alcohol use disorder (AUD) A random-effects meta-analysis of three studies [25,26,27] demonstrated that GLP-1RA use was associated with a significantly lower risk of AUD diagnosis compared with nonGLP-1RA comparators (HR = 0.72, 95% CI: 0.590.89, p = 0.0019)

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Only 20 out of the 44 approvals were granted to large or well-established biopharmaceutical companies, confirming an recent trend where emerging biotechnology companies develop a strategy to file by themselves, in the US, to maximise the value of their assets

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