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However patients often prefer to be sedated for a pain free procedure

Those are individualized, high-stakes conversations that require full disclosure, multidisciplinary collaboration, and explicit consent

VNS has been approved for the treatment of refractory epilepsy since 1997 and the treatment of resistant depression later

The challenge is knowing which is which

These drugs offer real promise for patients living with obesity and associated health problems, potentially changing lives by improving their mobility, alleviating joint pain, and reducing health complication risk factors

These changes generate a systemic and local milieu rich in metabolic substrates, hormones, and proinflammatory cytokines that fuel tumour growth