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This regimen is a starting point, and higher doses may be feasible as research progresses 1

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Pre-treatment of human and rat serum and urine samples Concentrations of L-CN and GBB in plasma and urine were determined in humans and rats using UHPLC/MS as previously described with minor modifications

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Dietary methionine intake alone is insufficient to meet the total requirement for SAM synthesis, necessitating additional synthesis catalyzed by vitamin B12 (67)