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For example, nitrogen balance was maintained in normal adult humans fed histidine-free diets for 8 days (Rose 1957), but there are no metabolic pathways for histidine synthesis in mammalian cells (Wu 2013)

which focused on the long-term efficacy of lycopene rather than its comparison with other therapeutic reagents (Kumar et al., 2007

These nutrients play roles in supporting energy production and liver function

However, herbal treatments also come with notable drawbacks, including a lack of regulation and standardization, which can lead to inconsistent efficacy and risks of contamination or misidentification

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The development of nanotechnology-based formulations, such as liposomes and nanophytosomes, has shown great promise in enhancing the solubility, stability, and brain bioavailability of these compounds, thereby maximizing their neuroprotective effects in ASD (Moghaddam et al., 2023