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GLP-1R agonists were initially used to treat T2DM and soon after it was found that these drugs possess many other physiological properties, such as neuroprotection, neurotrophic, and anti-inflammatory effects, which may be useful to slow the progression of AD ( Figure 3 ) ( Figure 3 Anti-inflammatory effects Previous studies have shown that GLP-1R mimics have anti-inflammatory effects in the CNS (139141)

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The Mechanism of Semaglutide Semaglutide, the main part of Ozempic, acts like GLP-1 in our bodies

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Apoptotic pathways can be divided into two categories: extrinsic apoptotic pathways triggered by cell death receptors, and intrinsic apoptotic pathways involving dysfunctional mitochondria [109]