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Hydroquinone is a prescription-strength bleaching agent that inhibits melanin production but carries risks including skin irritation, paradoxical darkening with prolonged use, and ochronosis with very long-term use

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In recent years, necroptosis, a novel subtype of regulated necrosis, and autophagy, a form of homeostatic housekeeping mechanism have witnessed a burgeoning interest owing to their potential to regulate and alleviate CP-induced AKI

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