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Alosetron use in clinical practice: significant improvement in irritable bowel syndrome symptoms evaluated using the US Food and Drug Administration composite endpoint

Groups at higher risk for B12 deficiency Certain people are biologically more likely to run low on B12, regardless of how healthy their diet seems

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Clinical trials show that response curves flatten at mid-range doses for many patientsmeaning the jump from 1.7 mg to 2.4 mg may add minimal benefit while increasing side effect risk

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