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Obesity significantly raises the risk of heart disease, diabetes, certain cancers, and premature death

Gradually increase load, speed, and repetitions toward pre-injury levels

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As a review in The Journal of Clinical Endocrinology & Metabolism describes, the warning specifically advises against these drugs for people with a personal or family history of medullary thyroid carcinoma or MEN2, a guidance rooted in rodent studies rather than common thyroid conditions