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Therapeutic strategies targeting SQOR must therefore be calibrated to the disease context
Systemic bioavailability of orally consumed glutathione is low because the molecule, a tripeptide, is the substrate of proteolytic enzymes (peptidases glutamyl transpeptidase GGT) of the alimentary canal, and because of the absence of a specific carrier of glutathione at the cell membrane site
Chen X, Niu J, Wang J, Zhao W (2022) Effects of L-carnitine Supplementation in High-Fat Diet on Growth, Antioxidant Capacity and Lipid Metabolism of Golden Pompano (Trachinotus ovatus)
These conversations matter because biology, evidence, and treatment choices are increasingly linked, and understanding that helps patients make sense of why options differ
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