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Different maximum dose

The peptide blocks NF-kB activation, a master switch for inflammatory gene expression

[] GLP-1 binds to the GLP-1 receptor (GLP-1R), a G-protein-coupled receptor, but is rapidly degraded by the enzyme dipeptidyl peptidase 4 (DPP4), giving it a short half-life

These specific molecules dictate cellular behavior across multiple biological systems

There is therefore considerable overlap between the potential actions of DPP4 on skeletal muscle and the actions of GLP-1 receptor agonists, and the data presented above in relation to GLP-1 receptor agonists are likely to be relevant

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