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In addition, data on suicide risk in patients on incretin therapies may be confounded by underlying conditions, including obesity and diabetes, which have been linked to increased suicide risk

There are two primary incretin hormones

Follow-up Repeat metabolic markers after 4-12 weeks, with closer review during dose escalation or major appetite changes

For those who require maximal weight loss, such as people managing severe obesity alongside cardiovascular risk or obstructive sleep apnoea, injectable therapy may remain the medically preferred route

This transition happens relatively quicklyoften within 2-4 weeksbecause your digestive system and brain hunger centers no longer have the chemical brake that tirzepatide provided

Most experts agree that 0.5 to 2.0 pounds per week, or roughly 1% of body weight, is appropriate