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This review also addresses an issue that has not been dealt with in a comprehensive manner and hopes to direct attention towards future research that will encompass patient-friendly therapeutic strategies, where drugs targeting co-activators will have enhanced benefits and reduced side effects

However, clinical studies are not limited to the radiologic appearance, but also several other parameters such as time for cast removal, range of motion, VAS or DASH scores, etc

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This is a direct, receptor-mediated effect that occurs independently of and in addition to the weight loss driven by reduced caloric intake

van Buuren S, Groothuis-Oudshoorn K