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Participants who completed a 36-week lead-in period showed a mean weight reduction of 20.9%, with those continuing tirzepatide reaching an overall reduction of 25.3% from baseline to week 88

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Tirzepatide has shown greater HbA1c reductions (2-2.5%) and more significant weight loss (15-20% of body weight) compared to Semaglutide, which typically results in a 1.5-2% reduction in HbA1c and 10-15% weight loss

DOI: 10.1016/S0140-6736(26)00802-0 Cite This Page : ScienceDaily