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Thymosin beta 4 is unusual in this compound class for having controlled human data, RGN-259 ophthalmic solution has been assessed in randomised, placebo-controlled, double-masked Phase 2 and Phase 3 trials in severe dry eye and neurotrophic keratopathy (Sosne et al., Cornea 2015 and Int J Mol Sci 2023)

Theres very little direct negotiation compared to other parts of the world, and the result is that patients pay the price. Acting as middlemen, PBMs negotiate drug prices on behalf of insurance companies and have been accused of prioritizing their profits over patient access

Side Effects: What to Expect and How We Help Serious but Rare Side Effects: Pancreatitis (stop medication, seek care if severe abdominal pain) Gallbladder issues (we monitor for symptoms) Allergic reactions (rare

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