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350 Although HDACis have neuroprotective effects in preclinical models, clinical trials of autophagy-focused therapies for the treatment of neurodegeneration are lacking

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Mazdutide Clinical Trial Results The GLORY trial program evaluated mazdutide across several Phase 3 studies

This dual action is what gives it such a formidable profile in studies related to glycemic control and weight management

Importantly, while weight loss was observed in these trials, the degree of improvement in cardiac outcomes were often disproportionate to the weight reduction alone, suggesting at weight loss-independent mechanisms 30,31,44