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Semaglutide can stay in the body for about four to five weeks after you inject it, says Kushner, but that doesnt necessarily mean its effects will last that long

223 European Medicines Agency

Minato, & S

Further, aGLP1-E2 exhibited improved insulin sensitivity compared to aGLP1 and iGLP1-E2 alone (HOMA-IR and insulin tolerance test)

Phentermine is FDA-approved for short-term use , generally no longer than 12 weeks (some studies extend to about six months), and it is a Schedule IV controlled substance meaning it has a proven but low potential for abuse and an accepted medical use