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Participants received one oral tablet containing 1000 g of cyanocobalamin (HealthAid, Co, UK) or a placebo (Barij Essence Co, Kashan, Iran) daily for 12 weeks

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Appendix Table A2 (online only) shows the prevalence of severe fatigue, significant depression, significant pain (defined as a score of 5 on any BPI item or being on analgesics at baseline), and carnitine deficiency by arm and time point