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SURMOUNT-MAINTAIN (Horn 2026, 112 weeks): continued top dose -21.9% vs 5 mg step-down -16.6% vs placebo -9.9%, rescue therapy 8/25/67%: Aronne JAMA 2024

Laboratories can use these aligned procurement characteristics to standardize how study arms are documented and repeated

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The measurements were then converted into a percentage using the following formula: % of wound remaining = (measurement at time 12 hours/measurement at time 0 hours) 100

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It also upregulates over 4,000 genes involved in tissue repair, angiogenesis, and antioxidant defense while downregulating pro-inflammatory and pro-fibrotic pathways