Looking closer at the data, Bloom's team found that changes in blood sugar control or weight while on the drugs had little to do with the relationship of metformin and GLP-1 use to improvements in asthma
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This result is in accordance with a previous report that a GLP-1 analog (exendin-4) enhanced excitatory synaptic transmission through AMPA receptors trafficking in the PVN CRH neurons (16) (Figure 1, G and H)
