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Moderate stage , where there is notable cartilage loss in weight bearing regions, along with meniscal degeneration, evidence of osteophytes and subchondral sclerosis, and weakening of the quadriceps muscles

The peptide successfully heals internal fistulas (gastrocutaneous, duodenocutaneous, and colocutaneous) in experimental models, achieving fistula closure even when treatment is delayed for one month after fistula formation

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Lippi et al

Biomaterial-based delivery systems (hydrogels) have been shown to be excellent carriers that enhance cell/drug localization, survival and therapeutic efficacy in organ injury repair

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