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Lower esophageal sphincter pressure assessment and pyloric sphincter pressure assessment As described before (10, 25, 41-43), in all rats, manometrical evaluation (cm H2O) was performed with a water manometer connected to the drainage port of the Foley catheter as described (the values of 68 76 cm H2O for lower esophageal sphincter, and 68 74 cm H2O for pyloric sphincter, were considered to be normal as determined before (10, 25, 41-43))

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