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Once the dose is increased to 0.5 mg per week after the first month, weight loss typically becomes evident

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Per Axios: "The states with the highest prescribing rates are also among those with greater prevalence of diabetes and obesity, per CDC data, a rough indication that the medicines may be getting to areas where they are in greatest need while shortages, high price tags and insurance restrictions have limited their use." (link) It will be interesting to see how the supply of these GLP-1 drugs go up as demand continues to soar