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Am J Pathol (2019) 189(11):225868

Doru, S., Yaar, E

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Arg is a substrate for several enzymatic reactions and is metabolized through three primary pathways: arginases which convert Arg into ornithine and urea, Arg decarboxylase which results in agmatine metabolites, and nitric oxide synthase (NOS) which uses Arg to produce NO and citrulline (Fig

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