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The pathophysiology of Long COVID, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and related dysautonomias shares a striking commonality: severe, persistent post-viral metabolic dysfunction

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All patients received a standard lifestyle intervention which included instruction on a reduced-calorie diet (approximately 500 kcal/day deficit) and increased physical activity counseling (recommended minimum of 150 min/week) that began with the first dose of ZEPBOUND, during the lead-in period, and continued throughout the trial

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