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Similarly, in the REWIND (Researching cardiovascular Events with a Weekly INcretin in Diabetes) CVOT, an exploratory mediation analysis suggested that HbA1c reduction accounted for approximately 50% of the beneficial effects of dulaglutide on stroke [21]

Roychowdhury S, McCullough RL, Sanz-Garcia C, Saikia P, Alkhouri N, Matloob A, et al

The effect typically peaks during dose escalation phases and diminishes as your body adapts

Green, R., & Kinsella, L

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The quality of that formulation is the single biggest determinant of how effective sublingual tirzepatide will be for your weight loss journey