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Capodanno, D., Alberts, M

The article adds that age, metabolic status and baseline metabolic syndrome severity also modulate side effect risk over months and years

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In the heart, zinc enhances cardiac mitochondrial function during reperfusion by ERK-dependent phosphorylation of STAT3 at Ser727, which translocates to mitochondria to upregulate ND6 and inhibit succinate dehydrogenase, reducing ROS generation 152

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