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Recent discoveries suggest that NNMT may play important roles in tissue-specific metabolic regulation beyond its established functions in liver and adipose tissue, including potential roles in brain metabolism, immune cell function, and tissue repair processes

[DOI] [PMC free article] [PubMed] [Google Scholar] 365.Modjtahedi BS, Do D, Luong TQ, Shaw J

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On the other hand, cancer cells often have high levels of iron and ROS due to their heightened metabolic activity to sustain uncontrolled cell growth