[DOI] [PubMed] [Google Scholar] Gibney J, Healy ML, Sonksen PH
Many beneficial biological effects are reported for probiotics belonging to the genera Lactobacillus and Bifidobacterium , particularly Lactococcus lactis , which has an antioxidative mechanism that involves scavenging oxidants, chelating metal ions, and preventing ROS formation [67,72]
It stimulates the release of insulin from the pancreas in a glucose-dependent manner (meaning it only releases insulin when blood sugar is high, reducing the risk of hypoglycemia) and suppresses the release of glucagon, a hormone that raises blood sugar
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However, these measures were often insufficient for achieving significant long-term body weight loss, and many patients experienced plateauing weight loss or struggled with weight regain after treatment discontinuation