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It has an acetyl group attached to L-Carnitine, which allows it to cross the blood-brain barrier for better absorption

Its cytoprotective effects on the intestinal lining have been consistently demonstrated in animal models across multiple decades of research.6 When taken orally, the peptide acts directly on the mucosal tissue it is designed to protect repairing tight junctions, reducing inflammatory cytokines, and supporting the microbiome environment

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Although there are many reasons an individual may experience a high level of homocysteine, consuming more methionine than what the body can handle in the methylation cycle may contribute to problems

The small sample size is also listed as another potential limitation of the study