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Moreover, although semaglutide did not induce regression of atherosclerosis, we were unable to detect any regression in mice switched back to a less atherogenic diet, limiting the available conclusions

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Monitoring nutrient status while on tirzepatide with B12 Baseline laboratory assessment before starting tirzepatide should include B12 levels, complete blood count (CBC), comprehensive metabolic panel (CMP), lipid panel, and HbA1c if you have diabetes or prediabetes