Discontinuation rates from the phase 2 trial due to side effects were generally low, though the broader literature on GLP-1 receptor agonists notes that discontinuation rates across the class can reach 20-50% within the first year
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Eduardo Grunvald, Medical Director of the University of California San Diego's Center for Advanced Weight Management, has noted, the more total weight you lose, the more muscle mass you tend to lose, though he is clear that the benefits of treating obesity outweigh that risk
Weight loss is not just about the number on the scale the type of weight lost and the nutrient deficiencies that may occur as a result of appetite suppression can pose serious health risks. Smith says that working closely with a healthcare team is essential for people who use the medications to ensure safety and efficacy
Does magnesium help GLP-1 side effects
10.1016/j.jacbts.2018.09.004 80 RiveraF