Definition and diagnostic criteria Hereditary glutathione synthetase deficiency is a rare autosomal recessive disease characterized by hemolytic anemia, metabolic acidosis, 5-oxoprolinuria, progressive neurological symptoms and recurrent bacterial infections
Physical trauma, known as the Koebner phenomenon, can induce the appearance of vitiligo patches in areas of repeated friction, wounds, scars, and pre-existing lesions of contact eczema or psoriasis.76 Exposure to chemicals, such as phenolic derivatives, generates a melanotoxic effect in vitiligo by inducing oxidative stress and causing direct damage to melanocytes
Most staggeringly, the high-dose group exhibited a massive 250% to 260% increase in exfoliated buccal mucosal (cheek) cells
Bao X, Siprashvili Z, Zarnegar BJ, Shenoy RM, Rios EJ, Nady N
Y., Lee, C
The risks of injecting unlicensed, often poorly manufactured compounds are real and not adequately offset by the potential benefits, particularly when well-evidenced alternatives are available