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It comes from how these drugs change the way you eat, hydrate, and move blood

GLP-1s (incretin mimetics) This type of medication works by increasing the levels of hormones called incretins

This leads to the accumulation of acetaldehyde in the body, causing adverse reactions such as nausea, vomiting, and palpitations, which help establish an aversive response to alcohol consumption (Heather, 1989)

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doi: 10.1016/j.cell.2014.11.047 101 YanoJ