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Description

Table 3 summarizes the pooled data on the gastrointestinal adverse reactions observed in the SURPASS-1 to SURPASS-5 studies for T2D therapy in comparison to placebo (61)

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The presence of GLP-1R in the phylogenetically oldest parts of the brain but not in the cortex emphasizes that GLP-1 is involved in the regulation of vital functions like feeding and satiety (141)