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The N-terminal tails of histones are targets for multiple modifications, including phosphorylation, methylation, acetylation, ubiquitination, poly ADP ribosylation, and sumoylation

Number of mice per treatment group = 10

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Cisplatin (CP) is one of the most effective antineoplastic drugs for the management of several solid-organ malignancies including Hodgkins and non-Hodgkins lymphomas, sarcomas, as well as head, lung, neck, bladder, breast, testicular, ovarian, and cervical cancers (Dasari and Bernard Tchounwou, 2014

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A combined blend is sometimes explored because repair biology is overlapping signals