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[8] One potential pathway appears to involve the activation of phospholipase C (PLC), which may lead to the release of inositol triphosphate (IP3) and diacylglycerol (DAG)

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A related study found that supplementing with 600 mg of alpha-lipoic acid for 10 days prior to noise exposure suggested some protection against changes in hearing measures compared to baseline, but the absence of a placebo group makes the results unreliable [26]

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PMID: 32257855