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Women should use additional contraception for 4 weeks after starting tirzepatide or increasing the dose, as it may reduce oral contraceptive effectiveness

Centaurea Cyanus Flower extract comes from the cornflower, Centaurea cyanus

human clinical trials are limited

Fighting extreme hunger with severe restriction will backfire, leading to binge episodes and potentially larger weight regain than a moderate approach

These gut-derived hormones are secreted in response to nutrient intake and are central to stimulating insulin release, lowering glucagon secretion, delaying gastric emptying, and modulating satiety

SCFAs are capable of traversing the blood-brain barrier to modulate central nervous system (CNS) activity, while dysregulation of microbiota-derived neurotransmitters, such as gamma-aminobutyric acid (GABA) and dopamine, is implicated in CNS disorders, including schizophrenia 35