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Most are sold without a prescription and contain herbal or supplement ingredients rather than the regulated GLP-1 medication found in prescription injections, which is why the category causes so much confusion

Rarely, people report pancreatitis or gallbladder problems

Magnesium has a mild stool-softening effect and is generally well-tolerated

Some telehealth providers charge a separate monthly fee for access to clinicians, messaging support, or their digital platform, on top of the medication cost itself

The FDA also raised concerns about contamination, incorrect dosages, unapproved or harmful ingredients, and counterfeit components in compounded GLP-1s

Especially, their analgesic effects are achieved without the development of tolerance, offering a significant advantage over traditional pain management strategies