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Appetite reduction is often the earliest noticeable effect, reported within the first one to two weeks due to GLP-1 activity on hypothalamic satiety signalling

Strength training protects your lean mass, supports healthy insulin levels, and keeps your metabolism humming

10.1126/sciimmunol.aar7754 17 FangY.JiL.ZhuC.XiaoY.ZhangJ.LuJ.et al (2020)

Multiple Endocrine Neoplasia Syndrome (MEN2) : Individuals with MEN2 are at increased risk for developing MTC and should also avoid GLP-1 medications

Cortisol and stress hormones Caloric restriction elevates cortisol

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