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If you carry an unfavorable GIPR tolerability variant, you may experience more nausea on this drug than on a GLP-1-only conjugate

In addition, further research is needed to clarify potential sex-specific differences and to better understand the central and peripheral mechanisms of action of GLP-1 and amylin analogues, including whether their effects are additive, synergistic, or potentially divergent in different clinical contexts

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N Engl J Med 2013;369:13271335

If symptoms do not improve or get worse, consider seeking medical advice

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