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Simonen M, Dali-Youcef N, Kaminska D, Venesmaa S, Kkel P, Pkknen M, Hallikainen M, Kolehmainen M, Uusitupa M, Moilanen L, Laakso M, Gylling H, Patti ME, Auwerx J, Pihlajamki J

After the intravenous injection of single doses (0.5 g) of LC, the plasma concentrations of ALC and LC returned to their initial values by 12 h [58]

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Modern pharmacologic approaches allow quantitative receptor engagement to be balanced, mitigating liabilities while preserving efficacy (Finan et al., 2016)