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N Engl J Med 358:25602572 The Action to Control Cardiovascular Risk in Diabetes Study Group (2008) Effects of intensive glucose lowering in type 2 diabetes

NAMPT-null mice have diminished NAD + synthesis and no other NAD biosynthetic enzymes

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Fras JP, Auerbach P, Bajaj HS et al (2021) Efficacy and safety of once-weekly semaglutide 20 mg versus 10 mg in patients with type 2 diabetes (SUSTAIN FORTE): a double-blind, randomised, phase 3B trial