Additionally, DAMPs promote the release of pro-inflammatory factors, such as IL-1, by mediating the assembly and activation of the NLRP3 inflammasome, thereby indirectly enhancing HSC activation and extracellular matrix accumulation [317]
2001.PMID Beck DE, et al
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Even light spotting should be reported to a healthcare provider
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doi: 10.3390/molecules27227832 392 YamasakiTTakeshitaSTomiyaCKoikedaT