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STEP 9 established that semaglutide can improve body weight and knee pain in people with obesity and KOA, and the TRIUMPH program indicates that newer incretin-based therapies are now being formally developed for obesity-related complications including knee osteoarthritis ( 8.2 Real-world and surgical-transition evidence now deserve priority A second priority is to define how these therapies perform in the transition zone between medical management and surgery

Understand the prescription-issuance cutoff

In late 2025, the oral Wegovy pill became available, offering an alternative for patients who prefer not to inject

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This helps you feel full for a longer period of time (satiety), which can lead to you eating less and losing weight

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