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Diabetes, heart disease, and some types of cancer are among the debilitating and deadly diseases associated with obesity

Efficacy of lifestyle interventions to treat pediatric obesity: A systematic review and multivariate meta-analysis of randomized controlled trials

This is partially mediated by weight loss (less body mass means less cardiovascular work) and partially by direct metabolic effects

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Clinical potential of fasting in type 1 diabetes

Dulaglutide (Trulicity): A once-weekly GLP-1 agonist for type 2 diabetes