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A: PPS are required to submit supporting evidence that demonstrates active engagement based on application commitments

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6%), gastritis (2%)

In hyperammonemia associated with urea cycle disorders, treatment with hemodialysis can reverse encephalopathy and prevent brain edema and death [36]

Serious side effects include signs of thyroid cancer, pancreatitis, kidney problems, gallbladder issues, and allergic reactions

However, the evidence for meaningful clinical benefit in elderly populations remains preliminary, and the risk-benefit calculation must account for potential effects on glucose metabolism and cancer risk